CancerDrs

Esophageal Cancer

Squamous cell carcinoma and adenocarcinoma of the esophagus. Trials explore combination chemoradiation, immunotherapy, and perioperative regimens.

21.9%
5-year relative survival
U.S. average across all stages
182
recruiting trials
Active in the U.S. right now
22,070
new diagnoses / year
You are not alone — roughly 60 people per day
69
median age at diagnosis
Most diagnoses occur in adults over age 50

Source: NCI SEER + ClinicalTrials.gov

Esophageal Cancer by the numbers (U.S.)

22,070
Estimated new cases (2025)
16,250
Estimated deaths (2025)
21.9%
5-year relative survival
69
Median age at diagnosis

Source: NCI SEER Cancer Stat Facts

Esophageal Cancer clinical trials →

182 actively recruiting trials across the U.S., with filters by state.

Second opinion for esophageal cancer →

Step-by-step for getting a virtual second opinion from a top cancer center.

NCI-designated cancer centers →

All 71 NCI cancer centers with hospital quality data and state browser.

Find a medical oncologist →

Licensed oncologists across every U.S. state, by specialty.

Financial aid resources →

Co-pay relief, drug patient-assistance, transportation, and lodging support.

Patient guides →

How to read a pathology report, questions to ask your oncologist, staging explained.

Also known as

esophageal carcinoma, GEJ cancer.

For deeper statistics

See the NCI SEER Cancer Stat Facts page: Esophageal Cancer on SEER →