Melanoma
The most serious form of skin cancer. Trials span adjuvant, neoadjuvant, and metastatic disease — with major advances in immunotherapy.
94.7%
5-year relative survival
U.S. average across all stages
251
recruiting trials
Active in the U.S. right now
104,960
new diagnoses / year
You are not alone — roughly 288 people per day
66
median age at diagnosis
Most diagnoses occur in adults over age 50
Source: NCI SEER + ClinicalTrials.gov
Melanoma by the numbers (U.S.)
104,960
Estimated new cases (2025)
8,430
Estimated deaths (2025)
94.7%
5-year relative survival
66
Median age at diagnosis
Source: NCI SEER Cancer Stat Facts
Melanoma clinical trials →
251 actively recruiting trials across the U.S., with filters by state.
Second opinion for melanoma →
Step-by-step for getting a virtual second opinion from a top cancer center.
NCI-designated cancer centers →
All 71 NCI cancer centers with hospital quality data and state browser.
Find a medical oncologist →
Licensed oncologists across every U.S. state, by specialty.
Financial aid resources →
Co-pay relief, drug patient-assistance, transportation, and lodging support.
Patient guides →
How to read a pathology report, questions to ask your oncologist, staging explained.
Also known as
skin cancer.
For deeper statistics
See the NCI SEER Cancer Stat Facts page: Melanoma on SEER →