Sarcoma second opinion
Getting a second opinion on a sarcoma diagnosis is a normal, recommended part of the decision-making process. Here's how to approach it, what records you'll need, and which centers have recognized expertise in sarcoma.
Sarcoma by the numbers (U.S.)
Source: NCI SEER Cancer Stat Facts
Why a second opinion matters for sarcoma
Rare cancers of bone and soft tissue. Many subtypes with distinct biology. Specialized sarcoma centers often run trials unavailable elsewhere.
Sarcoma treatment plans often involve multiple options — systemic therapy, surgery, radiation, immunotherapy, or combinations. A second opinion from a subspecialty expert can confirm the diagnosis, validate the plan, or introduce clinical-trial options you might not otherwise learn about.
What to prepare
- Pathology report and, if possible, pathology slides for re-review
- Imaging studies (CT, MRI, PET, ultrasound) on disc or via secure portal
- Operative notes (if you've had surgery)
- List of current medications and treatment history
- Name and contact info for your current oncologist
Where to get a sarcoma second opinion
Start with an NCI-designated cancer center — these institutions are recognized by the National Cancer Institute for research-led oncology care and typically have the deepest sarcoma subspecialty expertise. Most offer virtual second-opinion programs.
Look for: major comprehensive centers like MD Anderson, Memorial Sloan Kettering, Dana-Farber, Mayo Clinic, and Johns Hopkins; and regional NCI centers in your state (browse the full list).
Related resources on CancerDrs
Active recruiting sarcoma trials across the U.S.
NCI cancer centersAll 71 NCI-designated cancer centers, by state.
Find a hematologist-oncologistLicensed providers across the U.S.
Sarcoma statistics (SEER)Incidence + survival data from the NCI SEER program.