Phase 3 Recruiting Academic/Other
This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radi…
Sponsor: NRG Oncology
NCT ID: NCT04852887
Sites in Louisiana: - Ochsner Hematology Oncology North Shore - Covington (West Region) — Covington, Louisiana
- Louisiana State University Health Science Center — New Orleans, Louisiana
- Tulane University School of Medicine — New Orleans, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
- Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 3 Recruiting Academic/Other
This phase III trial compares 6 months of human epidermal growth factor receptor 2 (HER2)-targeted therapy to 12 months of HER2-targeted therapy for the treatment of HER2-positive (+) breast cancer in patients that had a pathologic complet…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT06876714
Sites in Louisiana: - Ochsner Hematology Oncology North Shore - Covington (West Region) — Covington, Louisiana
- Ochsner LSU Health Monroe Medical Center — Monroe, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
- Touro Infirmary — New Orleans, Louisiana
- Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 3 Recruiting NIH
This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint High 2 Risk (MP2) stage II-III hormone receptor positive, HER2 nega…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT06058377
Sites in Louisiana: - Ochsner LSU Health Monroe Medical Center — Monroe, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
- Touro Infirmary — New Orleans, Louisiana
- LSU Health Sciences Center at Shreveport — Shreveport, Louisiana
- Ochsner LSU Health - Cancer Treatment Center — Shreveport, Louisiana
Phase 3 Recruiting Academic/Other
NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and …
Sponsor: NRG Oncology
NCT ID: NCT06748222
Sites in Louisiana: - University Medical Center New Orleans — New Orleans, Louisiana
Phase 3 Recruiting Industry
This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurrence who…
Sponsor: AstraZeneca
NCT ID: NCT05952557
Sites in Louisiana: - Research Site — New Orleans, Louisiana
Phase 3 Recruiting Industry
This is a randomized, open-label study comparing the efficacy and safety of adjuvant sacituzumab tirumotecan (MK-2870) in combination with pembrolizumab compared to treatment of physician's choice (TPC) in participants with triple-negative…
Sponsor: Merck Sharp & Dohme LLC
NCT ID: NCT06393374
Sites in Louisiana: - CHRISTUS St. Frances Cabrini Hospital Center for Cancer Care ( Site 0109) — Alexandria, Louisiana
- Ochsner LSU Health - Monroe Medical Center, Family Medicine Clinic ( Site 0063) — Monroe, Louisiana
- Louisiana State University Health Sciences Shreveport ( Site 0029) — Shreveport, Louisiana
Phase 3 Recruiting Industry
This phase 3 clinical trial compares the safety and efficacy of palazestrant (OP-1250) to the standard-of-care options of fulvestrant or an aromatase inhibitor in women and men with breast cancer whose disease has advanced on one endocrine…
Sponsor: Olema Pharmaceuticals, Inc.
NCT ID: NCT06016738
Sites in Louisiana: - Clinical Trial Site — Baton Rouge, Louisiana
- Clinical Trial Site — New Orleans, Louisiana
Phase 3 Recruiting Industry
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth fa…
Sponsor: Merck Sharp & Dohme LLC
NCT ID: NCT06312176
Sites in Louisiana: - Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042) — Baton Rouge, Louisiana
Phase 2 Recruiting NIH
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally adva…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05564377
Sites in Louisiana: - East Jefferson General Hospital — Metairie, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
- Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 1, Phase 2 Recruiting Industry
This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2.
Sponsor: DualityBio Inc.
NCT ID: NCT05150691
Sites in Louisiana: - Women's Cancer Care — Covington, Louisiana
Phase 1, Phase 2 Recruiting Industry
This research study is studying a new compound, AZD8205, as a possible treatment for advanced or metastatic solid tumours alone or in combination with anti-cancer agents
Sponsor: AstraZeneca
NCT ID: NCT05123482
Sites in Louisiana: - Research Site — Shreveport, Louisiana
NA Recruiting Network
The purpose of this study is to evaluate feasibility and acceptability of completing PROs among AYAs randomized to Choice PRO vs Fixed PRO.
Sponsor: Eastern Cooperative Oncology Group
NCT ID: NCT05108298
Sites in Louisiana: - Louisiana State University Health Science Center — New Orleans, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
Recruiting Industry
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible …
Sponsor: Agendia
NCT ID: NCT03053193
Sites in Louisiana: - Louisiana State University — Shreveport, Louisiana
Recruiting Industry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…
Sponsor: Massive Bio, Inc.
NCT ID: NCT03452774
Sites in Louisiana: - Massive Bio SYNERGY-AI site — New Orleans, Louisiana
NA Recruiting Academic/Other
Most physicians still use a one-size-fits-all approach to breast screening in which all women, regardless of their personal history, family history or genetics (except BRCA carriers) are recommended to have annual mammograms starting at ag…
Sponsor: University of California, San Francisco
NCT ID: NCT02620852
Sites in Louisiana: - Louisiana State University — New Orleans, Louisiana
Recruiting Academic/Other
This study will determine how the intestinal microbiome differs between patients with obesity and early triple-negative breast cancer who achieve a pathologic complete response from preoperative anti-PD-1 immunotherapy (pembrolizumab) vers…
Sponsor: Pennington Biomedical Research Center
NCT ID: NCT06318507
Sites in Louisiana: - Pennington Biomedical Research Center — Baton Rouge, Louisiana