Leukemia clinical trials in District of Columbia

10 actively recruiting leukemia trials at 1 site across District of Columbia.

Data from ClinicalTrials.gov · last refreshed 2026-10-12

Phase 3 Recruiting NIH

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma.…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT04269902

Sites in District of Columbia:

MedStar Georgetown University Hospital — Washington D.C., District of Columbia
Sibley Memorial Hospital — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Phase 3 Recruiting Network

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs …

Sponsor: Children's Oncology Group

NCT ID: NCT04293562

Sites in District of Columbia:

MedStar Georgetown University Hospital — Washington D.C., District of Columbia
Children's National Medical Center — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Phase 3 Recruiting Industry

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

The purpose of this study is to evaluate the efficacy and safety of tacabrutideg alone compared with pirtobrutinib in patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who had…

Sponsor: BeOne Medicines

NCT ID: NCT06973187

Sites in District of Columbia:

Medstar Georgetown University Hospital — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Phase 2 Recruiting NIH

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

This phase II trial tests the addition of venetoclax and/or blinatumomab to usual chemotherapy for treating infants with newly diagnosed acute lymphoblastic leukemia (ALL) with a KMT2A gene rearrangement (KMT2A-rearranged \[R\]) or without…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT06317662

Sites in District of Columbia:

Children's National Medical Center — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Phase 1, Phase 2 Recruiting Academic/Other

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

This clinical trial will test the safety and efficacy of combining trametinib and azacitidine in patients with juvenile myelomonocytic leukemia (JMML). Newly diagnosed lower-risk JMML patients will receive trametinib and azacitidine. High-…

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

NCT ID: NCT05849662

Sites in District of Columbia:

Children's National Medical Center — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Phase 1, Phase 2 Recruiting Academic/Other

Phase IB/II of CPX-351 for Relapse Prevention in AML

This is a phase IB/II study with a 3+3 dose de-escalation study design. Patients will continue maintenance treatment with CPX-351 for 6 cycles on D1 and D3, as long as patient remains in CR. The dose de-escalation will be one dose given on…

Sponsor: Georgetown University

NCT ID: NCT04990102

Sites in District of Columbia:

Georgetown Lombardi Comprehensive Cancer Center — Washington D.C., District of Columbia

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Phase 1 Recruiting Academic/Other

Pilot Imaging Study of Leukemia

This is a prospective pilot study, the primary aim of which is to determine whether the presence of 18F FLT imaging signal uptake abnormalities correlate with clinically validated evidence of hematopoietic malignant disease (e.g. MRD, mole…

Sponsor: University of Oklahoma

NCT ID: NCT03633955

Sites in District of Columbia:

Children's National Health System — Washington D.C., District of Columbia

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Phase 1 Recruiting Academic/Other

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

This Phase I dose-escalation trial is designed to evaluate the safety of administering rapidly -generated tumor multi-antigen associated -specific cytotoxic T lymphocytes, to HSCT recipients with high risk AML and MDS.

Sponsor: Catherine Bollard

NCT ID: NCT02203903

Sites in District of Columbia:

Childrens National Medical Center — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

NA Recruiting NIH

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

Background: Chimeric antigen receptor T-cell (CART) therapy is a form of immunotherapy which can be used to treat people with relapsed B-ALL. For those who achieve remission after CART alone, it may cure up to 50% of people who receive thi…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT05621291

Sites in District of Columbia:

Children's National Medical Center — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

NA Recruiting Academic/Other

Virtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia

Over 90% of children and adolescents diagnosed with acute lymphoblastic leukemia (ALL) will survive long term. Part of the successful treatment that patients receive is the delivery of chemotherapy directly into their spinal fluid via a sp…

Sponsor: Children's National Research Institute

NCT ID: NCT06722638

Sites in District of Columbia:

Children's National Hospital — Washington D.C., District of Columbia

View on ClinicalTrials.gov →

Medical disclaimer: This page aggregates public ClinicalTrials.gov data. It is not medical advice. Always confirm eligibility and enrollment details with the trial site or your oncologist.

Source: ClinicalTrials.gov API v2 · Last checked: 2026-10-12