Phase 3 Recruiting NIH
This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma.…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT04269902
Sites in Louisiana: - Hematology/Oncology Clinic PLLC — Baton Rouge, Louisiana
- Ochsner LSU Health Monroe Medical Center — Monroe, Louisiana
- Tulane University School of Medicine — New Orleans, Louisiana
- Ochsner LSU Health Saint Mary's Medical Center — Shreveport, Louisiana
- LSU Health Sciences Center at Shreveport — Shreveport, Louisiana
Phase 3 Recruiting NIH
This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stag…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05675410
Sites in Louisiana: - Children's Hospital New Orleans — New Orleans, Louisiana
- Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 3 Recruiting Academic/Other
This phase III trial compares the effect of vorasidenib to placebo in combination with usual treatment, temozolomide, in treating patients with newly diagnosed grade 3 astrocytoma after radiation. Temozolomide is in a class of medications …
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT07215910
Sites in Louisiana: - West Jefferson Medical Center — Marrero, Louisiana
- East Jefferson General Hospital — Metairie, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
- Children's Hospital New Orleans — New Orleans, Louisiana
Phase 3 Recruiting Industry
The goal of this study is to compare how well sonrotoclax plus obinutuzumab works versus venetoclax plus rituximab in treating adults with relapsed and/or refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). …
Sponsor: BeOne Medicines
NCT ID: NCT06943872
Sites in Louisiana: - Mary Bird Perkins Cancer Center — Baton Rouge, Louisiana
Phase 3 Recruiting Industry
The purpose of Part 1 of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL; participants may or may not have already had treatment for their cancer. The purpose of Part …
Sponsor: Loxo Oncology, Inc.
NCT ID: NCT05254743
Sites in Louisiana: - Hematology Oncology Clinic — Baton Rouge, Louisiana
- Tulane Cancer Center Office of Clinical Research — New Orleans, Louisiana
Phase 2 Recruiting NIH
This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT04546399
Sites in Louisiana: - Children's Hospital New Orleans — New Orleans, Louisiana
- Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 2 Recruiting NIH
This phase II trial tests how well venetoclax, ibrutinib, prednisone, obinutuzumab, and Revlimid® (ViPOR) works in treating patients with CD10 negative diffuse large B-cell lymphoma (DLBCL) and high-grade lymphoma with MYC and BCL2 rearran…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT06649812
Sites in Louisiana: - Ochsner Medical Center Jefferson — New Orleans, Louisiana
Phase 2 Recruiting Industry
Researchers are looking for ways to treat germinal center B-cell-like diffuse large B-cell lymphoma (GCB DLBCL). DLBCL is a fast-growing blood cancer that affects B-cells. GCB is a type of DLBCL that affects young B-cells that are still ma…
Sponsor: Merck Sharp & Dohme LLC
NCT ID: NCT06890884
Sites in Louisiana: - Our Lady of the Lake Physician Group-Medical Oncology ( Site 0180) — Baton Rouge, Louisiana
- Ochsner LSU Health - Monroe Medical Center, Family Medicine Clinic ( Site 0209) — Monroe, Louisiana
- Ochsner Clinic Foundation ( Site 0189) — New Orleans, Louisiana
- Louisiana State University Health Sciences Shreveport ( Site 0195) — Shreveport, Louisiana
Phase 1, Phase 2 Recruiting Industry
Study consists of two main parts to explore BGB-16673 recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and monotherapy safety expansion of selected doses, and a Phase 2 (expansion cohorts)
Sponsor: BeOne Medicines
NCT ID: NCT05006716
Sites in Louisiana: - Mary Bird Perkins Cancer Center — Baton Rouge, Louisiana
Phase 2 Recruiting Industry
This is a Phase 2b, randomized, open label study to assess the safety and efficacy of DPX-Survivac and pembrolizumab, with and without low-dose cyclophosphamide (CPA) in subjects with relapsed or refractory DLBCL.
Sponsor: ImmunoVaccine Technologies, Inc. (IMV Inc.)
NCT ID: NCT04920617
Sites in Louisiana: - Tulane Cancer Center Office of Clinical Research — New Orleans, Louisiana
Phase 1 Recruiting NIH
This phase I trial tests the safety, side effects, best dose and effectiveness of lenalidomide when added to nivolumab and the usual drugs (rituximab and methotrexate) in patients with primary central nervous system (CNS) lymphoma. Lenalid…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT04609046
Sites in Louisiana: - LSU Health Baton Rouge-North Clinic — Baton Rouge, Louisiana
- Our Lady of the Lake Physician Group — Baton Rouge, Louisiana
NA Recruiting Network
The purpose of this study is to evaluate feasibility and acceptability of completing PROs among AYAs randomized to Choice PRO vs Fixed PRO.
Sponsor: Eastern Cooperative Oncology Group
NCT ID: NCT05108298
Sites in Louisiana: - Louisiana State University Health Science Center — New Orleans, Louisiana
- University Medical Center New Orleans — New Orleans, Louisiana
Recruiting Industry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…
Sponsor: Massive Bio, Inc.
NCT ID: NCT03452774
Sites in Louisiana: - Massive Bio SYNERGY-AI site — New Orleans, Louisiana
Phase 4 Recruiting Academic/Other
The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) risk category is being determined. The term "risk" refers to the chance of the AL…
Sponsor: St. Jude Children's Research Hospital
NCT ID: NCT06289673
Sites in Louisiana: - Our Lady of the Lakes Regional Medical Center — Baton Rouge, Louisiana
NA Recruiting Academic/Other
This is a multicenter study to test a decision-making support process for families and clinicians facing decisions about chronic home ventilation for a child. The investigators hypothesize that the intervention will increase family prepare…
Sponsor: Johns Hopkins University
NCT ID: NCT06102330
Sites in Louisiana: - Children's Hospital New Orleans — New Orleans, Louisiana