Phase 1, Phase 2 Recruiting Industry
Phase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2 dose (RP2D) of repotrectinib given to adult subjects with adv…
Sponsor: Turning Point Therapeutics, Inc.
NCT ID: NCT03093116
Sites in Florida: - Memorial Healthcare System — Hollywood, Florida
- Local Institution - 2113 — Tampa, Florida
Phase 1, Phase 2 Recruiting Industry
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer having a specific KRAS mutation. This is an open-label study which means that participants a…
Sponsor: Arvinas Inc.
NCT ID: NCT07023731
Sites in Florida: - Clinical Trial Site — Tampa, Florida
Phase 1, Phase 2 Recruiting Industry
This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.
Sponsor: ModeX Therapeutics, An OPKO Health Company
NCT ID: NCT06239194
Sites in Florida: - Sylvester Comprehensive Cancer Center - University of Miami Health System — Miami, Florida
Phase 2 Recruiting Industry
To assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET fusion, primary CN…
Sponsor: Apollomics Inc.
NCT ID: NCT03175224
Phase 2 Recruiting Academic/Other
This research is being done to determine the efficacy of selpercatinib to restore radioactive iodine (I-131 NaI) uptake and allow for I-131 treatment in people with RET fusion-positive radioiodine-refractory thyroid cancer. This research s…
Sponsor: Massachusetts General Hospital
NCT ID: NCT05668962
Sites in Florida: - Moffitt Cancer Center — Tampa, Florida
Phase 1 Recruiting Industry
The purpose of this clinical trial is to learn the safety and effects of the study medicine (PF-07799544) alone or in combination as a potential cancer treatment for adults with advanced solid tumors. The study will be conducted in two par…
Sponsor: Pfizer
NCT ID: NCT05538130
Sites in Florida: - Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center — Tampa, Florida
- Moffitt Cancer Center — Tampa, Florida
- Moffitt McKinley Hospital — Tampa, Florida
Phase 1 Recruiting Industry
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07799933) administered as a single agent and in combination with other study medicines in people with solid tumors. This study is …
Sponsor: Pfizer
NCT ID: NCT05355701
Sites in Florida: - Sylvester Comprehensive Cancer Center — Miami, Florida
- University of Miami Hospital and Clinics — Miami, Florida
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in Florida: - Mount Sinai Comprehensive Cancer Center at Aventura — Aventura, Florida
- Schulze Family Foundation Cancer Clinic - Bonita Health Center — Bonita Springs, Florida
- Morton Plant Hospital — Clearwater, Florida
- Broward Health North — Deerfield Beach, Florida
- Holy Cross Hospital — Fort Lauderdale, Florida
Recruiting Academic/Other
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, h…
Sponsor: University of Nebraska
NCT ID: NCT02012699
Sites in Florida: - Florida Hospital Memorial Medical Center — Daytona Beach, Florida
- Florida Hospital DeLand — DeLand, Florida
- Florida Hospital FISH — Orange City, Florida
- Florida Hospital Flagler — Palm Coast, Florida
- Tallahassee Memorial Hospital — Tallahassee, Florida
Recruiting Industry
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, …
Sponsor: Adela, Inc
NCT ID: NCT05366881
Sites in Florida: - Miami Cancer Institute — Miami, Florida
Recruiting Industry
This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease and have n…
Sponsor: AstraZeneca
NCT ID: NCT07124000
Sites in Florida: - Research Site — Coral Springs, Florida
- Research Site — Fort Myers, Florida
- Research Site — Palm Harbor, Florida
NA Recruiting Industry
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof. Stefano Spiezia, MD (Ospedale del Mare, Naples, Italy) and to monitor additional thyr…
Sponsor: Pulse Biosciences, Inc.
NCT ID: NCT07287176
Sites in Florida: - Sarasota Memorial Hospital — Sarasota, Florida
Recruiting Academic/Other
This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
Sponsor: Mayo Clinic
NCT ID: NCT06207188
Sites in Florida: - Mayo Clinic in Florida — Jacksonville, Florida
NA Recruiting Academic/Other
This study is to evaluate the effectiveness of nsPFA in treating papillary thyroid microcarcinoma. T
Sponsor: M.D. Anderson Cancer Center
NCT ID: NCT07218315
Sites in Florida: - Sarasota Memorial Hospital — Sarasota, Florida
Recruiting Academic/Other
The objective of this study is to demonstrate the clinical utility of I-124 PET/CT imaging and dosimetry in patients with thyroid cancer including 1) Evaluation of extent (volume and pattern) of remnant tissue in post total thyroidectomy s…
Sponsor: Miami Cancer Research Center, Inc.
NCT ID: NCT06443866
Sites in Florida: - Miami Cancer Research Center — North Miami, Florida