Multiple Myeloma second opinion
Getting a second opinion on a multiple myeloma diagnosis is a normal, recommended part of the decision-making process. Here's how to approach it, what records you'll need, and which centers have recognized expertise in multiple myeloma.
Multiple Myeloma by the numbers (U.S.)
Source: NCI SEER Cancer Stat Facts
Why a second opinion matters for multiple myeloma
Plasma cell malignancy. Trials test CAR-T, bispecific antibodies, and combination regimens in newly diagnosed and relapsed/refractory settings.
Multiple Myeloma treatment plans often involve multiple options — systemic therapy, surgery, radiation, immunotherapy, or combinations. A second opinion from a subspecialty expert can confirm the diagnosis, validate the plan, or introduce clinical-trial options you might not otherwise learn about.
What to prepare
- Pathology report and, if possible, pathology slides for re-review
- Imaging studies (CT, MRI, PET, ultrasound) on disc or via secure portal
- Operative notes (if you've had surgery)
- List of current medications and treatment history
- Name and contact info for your current oncologist
Where to get a multiple myeloma second opinion
Start with an NCI-designated cancer center — these institutions are recognized by the National Cancer Institute for research-led oncology care and typically have the deepest multiple myeloma subspecialty expertise. Most offer virtual second-opinion programs.
Look for: major comprehensive centers like MD Anderson, Memorial Sloan Kettering, Dana-Farber, Mayo Clinic, and Johns Hopkins; and regional NCI centers in your state (browse the full list).
Related resources on CancerDrs
Active recruiting multiple myeloma trials across the U.S.
NCI cancer centersAll 71 NCI-designated cancer centers, by state.
Find a hematologist-oncologistLicensed providers across the U.S.
Multiple Myeloma statistics (SEER)Incidence + survival data from the NCI SEER program.