Phase 3 Recruiting Network
This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in diff…
Sponsor: ECOG-ACRIN Cancer Research Group
NCT ID: NCT03937635
Locations: - University of Alabama at Birmingham Cancer Center — Birmingham, Alabama
- Anchorage Associates in Radiation Medicine — Anchorage, Alaska
- Anchorage Radiation Therapy Center — Anchorage, Alaska
+ 698 more sites in the U.S.
Phase 3 Recruiting Network
This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of c…
Sponsor: ECOG-ACRIN Cancer Research Group
NCT ID: NCT04566328
Locations: - Anchorage Associates in Radiation Medicine — Anchorage, Alaska
- Anchorage Radiation Therapy Center — Anchorage, Alaska
- Alaska Breast Care and Surgery LLC — Anchorage, Alaska
+ 590 more sites in the U.S.
Phase 3 Recruiting Network
This phase III trial compares three-drug induction regimens followed by double-or single-drug maintenance therapy for the treatment of newly diagnosed multiple myeloma in patients who are not receiving a stem cell transplant and are consid…
Sponsor: SWOG Cancer Research Network
NCT ID: NCT05561387
Locations: - Anchorage Associates in Radiation Medicine — Anchorage, Alaska
- Anchorage Radiation Therapy Center — Anchorage, Alaska
- Alaska Breast Care and Surgery LLC — Anchorage, Alaska
+ 394 more sites in the U.S.
Phase 3 Recruiting Industry
The purpose of this study is to learn about the study medicine called elranatamab.This study aims to compare elranatamab to other medicines for the treatment of MM (a type of cancer). This study is seeking participants who: * Are 18 years …
Sponsor: Pfizer
NCT ID: NCT06152575
Locations: - Infirmary Cancer Care — Mobile, Alabama
- Western Regional Medical Center, Inc. dba. City of Hope Phoenix — Goodyear, Arizona
- Beverly Hills Cancer Center — Beverly Hills, California
+ 92 more sites in the U.S.
Phase 3 Recruiting Industry
The purpose of this study is to compare the efficacy of teclistamab in combination with daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexam…
Sponsor: Janssen Research & Development, LLC
NCT ID: NCT05552222
Locations: - Banner MD Anderson Cancer Center — Gilbert, Arizona
- University of Arizona Cancer Center — Tucson, Arizona
- UCSF Fresno — Clovis, California
+ 58 more sites in the U.S.
Phase 3 Recruiting Industry
The purpose of this study is to compare the efficacy and safety of mezigdomide (CC-92480), bortezomib and dexamethasone (MeziVd) versus pomalidomide, bortezomib and dexamethasone (PVd) in participants with relapsed or refractory multiple m…
Sponsor: Celgene
NCT ID: NCT05519085
Locations: - Cancer and Blood Specialty Clinic — Los Alamitos, California
- Sharp Memorial Hospital — San Diego, California
- Local Institution - 0273 — West Hollywood, California
+ 53 more sites in the U.S.
Phase 3 Recruiting Industry
The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, inclu…
Sponsor: Kite, A Gilead Company
NCT ID: NCT06413498
Locations: - Banner MD Anderson Cancer Center — Gilbert, Arizona
- Mayo Clinic Hospital — Gilbert, Arizona
- City of Hope (City of Hope National Medical Center, City of Hope Medical Center) — Duarte, California
+ 47 more sites in the U.S.
Phase 3 Recruiting Industry
The purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dex…
Sponsor: Janssen Research & Development, LLC
NCT ID: NCT06208150
Locations: - UCSF Fresno — Clovis, California
- UCLA — Santa Monica, California
- Yale University School Of Medicine — New Haven, Connecticut
+ 46 more sites in the U.S.
Phase 3 Recruiting Industry
Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections, weaker bones, and kidney fail…
Sponsor: AbbVie
NCT ID: NCT06158841
Locations: - University of Alabama at Birmingham - Main /ID# 261434 — Birmingham, Alabama
- Mayo Clinic Hospital - Phoenix /ID# 263326 — Phoenix, Arizona
- Alta Bates Summit Medical Center for Research /ID# 261438 — Berkeley, California
+ 43 more sites in the U.S.
Phase 3 Recruiting Industry
The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).
Sponsor: Bristol-Myers Squibb
NCT ID: NCT05827016
Locations: - Rocky Mountain Cancer Centers — Aurora, Colorado
- Mayo Clinic Florida — Jacksonville, Florida
- Tampa General Hospital — Tampa, Florida
+ 41 more sites in the U.S.
Phase 3 Recruiting Industry
This is a randomised, multicentre, controlled, open-label, Phase III global study comparing the efficacy and safety of AZD0120 versus standard regimens (DKd \[daratumumab, carfilzomib, and dexamethasone\], DPd \[daratumumab, pomalidomide, …
Sponsor: AstraZeneca
NCT ID: NCT07391657
Locations: - Research Site — Gilbert, Arizona
- Research Site — Phoenix, Arizona
- Research Site — Tucson, Arizona
+ 38 more sites in the U.S.
Phase 3 Recruiting Network
This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone as …
Sponsor: European Myeloma Network B.V.
NCT ID: NCT05243797
Locations: - Banner University Medical Center Tucson, University of Arizona — Phoenix, Arizona
- UCLA Medical Center — Los Angeles, California
- University of California-Davis Cancer Center — Sacramento, California
+ 37 more sites in the U.S.