Colorectal Cancer clinical trials in South Carolina

9 actively recruiting colorectal cancer trials at 16 sites across South Carolina.

Data from ClinicalTrials.gov · last refreshed 2026-04-20

Phase 3 Recruiting Network

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

This phase III trial evaluates whether a web-based intervention called Current Together after Cancer (CTAC) works to increase the number of patients with surgically removed (resected) colorectal cancer who receive surveillance care that al…

Sponsor: SWOG Cancer Research Network

NCT ID: NCT07018869

Sites in South Carolina:

Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina
Ralph H Johnson VA Medical Center — Charleston, South Carolina
Medical University of South Carolina — Charleston, South Carolina
Prisma Health Cancer Institute - Easley — Easley, South Carolina
Gibbs Cancer Center-Gaffney — Gaffney, South Carolina

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Phase 1, Phase 2 Recruiting Industry

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tumors harboring a TP53 Y220C mutation. Th…

Sponsor: PMV Pharmaceuticals, Inc

NCT ID: NCT04585750

Sites in South Carolina:

Medical University of South Carolina — Charleston, South Carolina

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Phase 1, Phase 2 Recruiting Industry

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus on Colorectal carcinoma (CRC).

Sponsor: Apollo Therapeutics Ltd

NCT ID: NCT06399757

Sites in South Carolina:

Medical University of South Carolina — Charleston, South Carolina

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Phase 1 Recruiting Industry

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect of biomarkers of zanzalintinib administered alon…

Sponsor: Exelixis

NCT ID: NCT05176483

Sites in South Carolina:

Exelixis Clinical Site #9 — Myrtle Beach, South Carolina

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Phase 1 Recruiting Industry

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy (HLA-G inhibitor) and in combination with either pembrolizum…

Sponsor: Tizona Therapeutics, Inc

NCT ID: NCT04485013

Sites in South Carolina:

Medical University of South Carolina — Charleston, South Carolina

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Phase 1 Recruiting Industry

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

The main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in participants with advanced or metastatic solid tumors.

Sponsor: Coherus Oncology, Inc.

NCT ID: NCT06657144

Sites in South Carolina:

Prisma Health Cancer Institute — Greenville, South Carolina

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Recruiting Academic/Other

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…

Sponsor: Alliance for Clinical Trials in Oncology

NCT ID: NCT05334069

Sites in South Carolina:

AnMed Health Cancer Center — Anderson, South Carolina
Prisma Health Richland Hospital — Columbia, South Carolina
McLeod Regional Medical Center — Florence, South Carolina
Gibbs Cancer Center-Gaffney — Gaffney, South Carolina
Tidelands Georgetown Memorial Hospital — Georgetown, South Carolina

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Recruiting Industry

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…

Sponsor: Massive Bio, Inc.

NCT ID: NCT03452774

Sites in South Carolina:

Massive Bio SYNERGY-AI site — Greenville, South Carolina

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NA Recruiting Academic/Other

Resistance Exercise and Creatine in Colorectal Cancer

skeletal muscle mass and function, is prevalent in up to 60% of colorectal cancer patients. This condition arises from a combination of factors such as aging, inactivity, treatment side effects, malnutrition, tumor burden, and inflammation…

Sponsor: University of South Carolina

NCT ID: NCT06420726

Sites in South Carolina:

University of South Carolina — Columbia, South Carolina

View on ClinicalTrials.gov →

Medical disclaimer: This page aggregates public ClinicalTrials.gov data. It is not medical advice. Always confirm eligibility and enrollment details with the trial site or your oncologist.

Source: ClinicalTrials.gov API v2 · Last checked: 2026-04-20